I have beautiful comfrey plants in my garden and I use them for making soil fertilizer. Herbalist here in France where I live are well aware of the pyrrolizidine alkaloids toxicity dangers, but mostly mention the dangers of consuming it. Comfrey is an amazing plant, but I agree that it isn’t without serious toxicity risks. People die of eating too much salt and that is sitting on your table. It is safe to use externally.Īnd please amend this article. Simply – don’t use comfrey internally unless it’s an emergency. THEN – absorption rate of pyrrolizidine alkaloid lycopsamine in symphytum officinale through skin is POOR And the leaves of the cultivated comfrey may not have any detectable alkaloids present. Secondly, the ROOT contains more alkaloids than leaves. Main difference – wild comfrey (yellow flowers) contains higher amount of alkaloids than cultivated comfrey (violet/blue flowers). Please see the studies below as reference (there are many more). Then I researched a bit – and this article is simply an unpleasant scare crow. 1991 23:35-8.Īfter reading this article I freaked out a bit as I have been treating my 1.5 yr old daughter mosquito bites and bruises with comfrey cream and juice from leaves (external use only). The effects of comfrey derived pyrrolizidine alkaloids on rat liver. Hepatocyte membrane injury and bleb formation following low dose comfrey toxicity in rats. Determination of pyrrolizidine alkaloids in commercial comfrey products ( Symphytum sp.). Analysis, separation, and bioassay of pyrrolizidine alkaloids from comfrey ( Symphytum officinale). Mutagenicity of comfrey ( Symphytum officinale) in rat liver. Toxicokinetics of riddelliine, a carcinogenic pyrrolizidine alkaloid, and metabolites in rats and mice. If you want my honest opinion, rather avoid Comfrey and any products containing it, altogether. Horses may have neurological signs such as “head pressing”
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